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. 2019 Sep 9;142(11):3502–3513. doi: 10.1093/brain/awz269

Figure 2.

Figure 2

Medium and long-range connections are implicated in IED-spindle coupling. (A) Number of electrodes expressing IEDs that couple to spindles across all patients divided by anatomical lobe. (B) Number of electrodes expressing spindles that are coupled to IEDs across all patients divided by lobe. (C) Number of IED-spindle pairs per brain region; lobes colour-coded as in A and B. Warmer colours indicate more pairs; ordered list of individual brain regions is in Supplementary Table 2. (D) Schematics showing the most prominent IED-spindle anatomical pairings across patients for each brain region expressing IEDs, separated by lobe and projected onto lateral and medial cortical surfaces (left hemisphere view; right hemisphere locations converted to left for display purposes). Origin of arrow indicates location of IED electrode; destination indicates location of coupled SPI electrode. White circles show location of each brain region and colours separate pairings of individual IED electrode locations. (E) Histogram of average distance between pairs of electrodes that interact via IED-spindle coupling. F = frontal; L = limbic; LT = lateral temporal; O = occipital; P = parietal; SPI = spindle.