Figure 6.

Maximal spindle spatial extent and travelling predict brain regions influenced by IEDs. (A) Region of maximal spindle spatial extent (left) and maximal spindle travelling modulation index (right) obtained by watershed analysis of a sample patient’s subdural grid. The regions representing the union between these measures are identified in blue (bottom). (B) Regions of significant spindle coupling (left) to IEDs generated at regions marked on the right for the same patient as in A. Regions of IED-spindle coupling are identified in yellow (bottom). (C) Overlap between regions of maximally extensive propagating spindles and regions expressing spindles coupled to IEDs (green). (D) Percentage of overlap between regions of maximally extensive propagating spindles and regions expressing spindles coupled to IEDs across all patients with >20 significant IED-spindle pairs (n = 8).