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. 2019 May 27;170(2):549–561. doi: 10.1093/toxsci/kfz122

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Published by Oxford University Press on behalf of the Society of Toxicology 2019.

This work is written by US Government employees and is in the public domain in the US.

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Figure 2. — Hepatic TGFβ1 signaling was increased in APAP-treated mice. A, Images of immunohistochemistry for TGFβ1 in liver sections from vehicle and time course APAP-treated mice. B, TGFβ1 concentration in liver homogenates from vehicle and APAP-treated time course mice as measured with ELISA. C, Serum TGFβ1 levels as measured by ELISA in samples from vehicle and time course APAP-treated mice. D, TGFβ1 concentration measured by ELISA in conditioned media from primary hepatocytes treated with the indicated doses of APAP. *p < .05 compared with vehicle-treated mice.