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. 2019 Jun 14;47(19):10134–10150. doi: 10.1093/nar/gkz515

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Published by Oxford University Press on behalf of Nucleic Acids Research 2019.

This work is written by (a) US Government employee(s) and is in the public domain in the US.

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Scheme 2. — Synthesis of 8-bromo-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (8) and 8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (9) (55,59,60).