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. 2019 Oct 30;14(10):e0224486. doi: 10.1371/journal.pone.0224486

Table 1. Baseline characteristics of patients according to their smoking habits.

Total
(n = 478248)
Never-smoker
(n = 327819)
Ex-smoker
(n = 43162)
Current smoker
(n = 107267)
p-value
Age (years) 54.27±9.60 55.07±9.72 53.36±91.41 52.20±8.92 < .001
Male sex 257028 (53.7%) 114225 (34.8%) 41161(95.4%) 101642 (94.8%) < .001
BMI (kg/m2) 23.99±2.98 24.05±3.01 24.26±2.76 23.69±2.95 < .001
SBP (mmHg) 127.08±17.84 126.76±18.16 128.38±16.71 127.56±17.27 < .001
DBP (mmHg) 79.33±11.47 78.82±11.53 80.68±11.06 80.34±11.35 < .001
Economic status, n (%) < .001
    Covered by medical aid 1549 (0.3%) 1107 (0.3%) 98 (0.2%) 344 (0.3%)
    First quintile (lowest) 75180 (15.7%) 55188 (16.8%) 4446 (10.3%) 15546 (14.5%)
    Second quintile 65576 (13.7%) 46963 (14.3%) 4396 (10.2%) 14217 (13.3%)
    Third quintile 75001 (15.7%) 50369 (15.4%) 5971 (13.8%) 18661 (17.4%)
    Fourth quintile 99116 (20.7%) 65833 (20.1%) 9327 (21.6%) 23956 (22.3%)
    Fifth quintile 161826 (33.8%) 108359 (33.1%) 18924 (43.8%) 34543 (32.2%)
Underlying disease (%)
    HTN 98342 (20.6%) 74105 (22.6%) 8725 (20.2%) 15512 (14.5%) < .001
    DM 28382 (5.9%) 19761 (6.0%) 2685 (6.2%) 5936 (5.5%) < .001
    Dyslipidemia 74339 (15.5%) 54672 (16.7%) 7107 (16.5%) 12560 (11.7%) < .001
    CKD 1445 (0.3%) 1093 (0.3%) 136 (0.3%) 216 (0.2%) < .001
Laboratory findings
    Total cholesterol (mg/dL) 199.76±37.78 200.30±37.91 199.38±36.80 198.26±37.71 < .001
    Fasting blood glucose (mg/dL) 98.47±31.76 97.55±30.65 100.05±29.53 100.67±35.58 < .001
    Hemoglobin (g/dL) 13.88±1.52 13.49±1.47 14.68±1.22 14.78±1.23 < .001
    AST 26.60±17.34 25.62±15.59 28.07±18.34 28.97±21.28 < .001
    ALT 25.40±20.26 23.74±18.62 29.06±22.98 29.00±23.05 < .001
Medication (%)
    Warfarin 482 (0.1%) 351 (0.1%) 64 (0.1%) 67 (0.1%) < .001
    Aspirin 19683 (4.1%) 14659 (4.5%) 1895 (4.4%) 3129 (2.9%) < .001
    Clopidogrel 917 (0.2%) 661 (0.2%) 117 (0.3%) 139 (0.1%) < .001
    Ticlopidine 551 (0.1%) 409 (0.1%) 55 (0.1%) 87 (0.1%) 0.001
    ACEi or ARB 26158 (5.5%) 19015 (5.8%) 2792 (6.5%) 4351 (4.1%) < .001
    Beta blocker 25399 (5.3%) 19273 (5.9%) 2198 (5.1%) 3928 (3.7%) < .001
    CCB 29717 (6.2%) 22103 (6.7%) 2761 (6.4%) 4853 (4.5%) < .001
    Statin 11931 (2.5%) 8923 (2.7%) 1175 (2.7%) 1833 (1.7%) < .001

BMI; body mass index, SBP; systolic blood pressure, DBP; diastolic blood pressure, HTN; hypertension, DM; diabetes mellitus, CKD; chronic kidney disease, AST; aspartate transaminase, ALT; alanine transaminase, ACEi; Angiotensin-converting enzyme inhibitor, ARB; Angiotensin receptor blocker, CCB; calcium channel blocker