Table 1.
Summary validation results
| Cohort | Locus | N | HLA*PRG |
Kourami |
xHLA |
HLA*LA |
||||
|---|---|---|---|---|---|---|---|---|---|---|
| Call rate | Accuracy | Call rate | Accuracy | Call rate | Accuracy | Call rate | Accuracy | |||
| Illumina WGS | A | 28 | 1.00 | 1.00 | 1.00 | 0.96 | 1.00 | 1.00 | 1.00 | 1.00 |
| B | 28 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |
| C | 28 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |
| DQA1 | 18 | 1.00 | 1.00 | 1.00 | 1.00 | 0.00 | NA | 1.00 | 1.00 | |
| DQB1 | 28 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |
| DRB1 | 28 | 1.00 | 0.96 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.96 | |
| Illumina exome | A | 58 | 1.00 | 0.86 | 0.76 | 0.91 | 1.00 | 0.98 | 1.00 | 0.93 |
| B | 48 | 1.00 | 0.85 | 0.63 | 0.87 | 1.00 | 0.88 | 1.00 | 0.92 | |
| C | 56 | 1.00 | 0.79 | 0.61 | 0.97 | 1.00 | 0.96 | 1.00 | 0.88 | |
| DQA1 | 58 | 1.00 | 0.95 | 1.00 | 0.97 | 0.00 | NA | 1.00 | 0.97 | |
| DQB1 | 58 | 1.00 | 0.98 | 0.97 | 0.96 | 1.00 | 0.95 | 1.00 | 0.98 | |
| DRB1 | 58 | 1.00 | 0.91 | 1.00 | 0.97 | 1.00 | 0.98 | 1.00 | 0.91 | |
| Long-read WGS | A | 6 | NA | NA | NA | 1.00 | 1.00 | |||
| B | 6 | 1.00 | 1.00 | |||||||
| C | 6 | 1.00 | 1.00 | |||||||
| DQA1 | 6 | 1.00 | 1.00 | |||||||
| DQB1 | 6 | 1.00 | 1.00 | |||||||
| DRB1 | 6 | 1.00 | 0.83 | |||||||
| Long-read targeted | A | 360 | NA | NA | NA | 1.00 | 1.00 | |||
| B | 362 | 1.00 | 1.00 | |||||||
| C | 362 | 1.00 | 1.00 | |||||||
| DQA1 | 318 | 1.00 | 0.97 | |||||||
| DQB1 | 362 | 1.00 | 0.97 | |||||||
| DRB1 | 280 | 1.00 | 0.95 | |||||||