TABLE 1.
Subject baseline characteristics, shown by intervention1
| Characteristic | 40% fat (n = 10) | 0% fat (n = 10) | 0% fat-fast (n = 7) |
|---|---|---|---|
| Age, y | 23 (19–32) | 24 (19–32) | 23 (19–33) |
| Body weight, kg | 60 (48–75) | 65 (57–75) | 66 (58–77) |
| BMI, kg/m2 | 22 (17–25) | 24 (21–26) | 24 (22–27) |
| Body fat,2 % | 31 (14–45) | 34 (23–45) | 36 (23–45) |
| Blood pressure (systolic), mm Hg | 106 (96–121) | 112 (96–120) | 112 (103–120) |
| Blood pressure (diastolic), mm Hg | 67 (45–76) | 66 (53–75) | 67 (55–80) |
| Total cholesterol, mg/dL | 145 (96–195) | 151 (101–190) | 170 (115–195) |
| Triglycerides, mg/dL | 76 (38–120) | 58 (32–204) | 62 (45–86) |
| HDL cholesterol, mg/dL | 60 (35–82) | 59 (38–74) | 61 (38–82) |
| LDL cholesterol, mg/dL | 72 (40–102) | 72 (56–110) | 89 (66–120) |
| Glucose, mg/dL | 88 (78–99) | 91 (80–97) | 90 (73–91) |
| Hematocrit, % | 36 (31–40) | 36 (32–39) | 36 (33–38) |
| 8-IsoPGF2a,3 ng/g creatinine | 0.38 (0.22–0.63) | 0.41 (0.16–0.77) | 0.35 (0.25–0.75) |
| Prostaglandin F2a,3 ng/g creatinine | 1.12 (0.83–2.73) | 1.29 (0.47–2.51) | 1.24 (0.57–2.05) |
Values are medians (ranges). Intervention groups included the following participants: 40% fat (n = 10), subject numbers 1 to 9 and 12; 0% fat (n = 10), subject numbers 1 to 5, 8 to 11, and 13; and 0% fat-fast (n = 7), subject numbers 1, 2, 4, 5, 9, 10, and 11. Five women participated in all 3 interventions, subject numbers 1, 2, 4, 5, and 9. The medians were calculated from the baseline data of the individuals participating in that group.
Body fat was determined by dual-energy X-ray absorptiometry whole-body composition analyses (Hologic Discovery QDR; Hologic).
Urinary isoprostanes measured as described (18). Values shown in the table are within the ranges for nonsmoking, healthy women.