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. 2019 Sep 9;110(5):1148–1167. doi: 10.1093/ajcn/nqz172

TABLE 7.

Fecal d0-γ-T, d0-, d3-, and d6-α-T excreted1

Paired subjects (n = 6)
 Characteristic 40% fat 0% fat  P value
d0-γ-T 33 ± 7 42 ± 14 0.4125
d0-α-T 22 ± 4 17 ± 3 0.3844
d3-α-T 9.9 ± 1.9 8.8 ± 1.2 0.6589
d6-α-T 0.59 ± 0.20 0.66 ± 0.09 0.7504
Percent dose d3-α-T excreted2 33% ± 6% 29% ± 4% 0.6568
d3-α-T fractional absorption3 67% ± 6% 71% ± 4% 0.6568
Percent dose d6-α-T excreted4 2.0% ± 0.6% 2.2% ± 0.3% 0.7516
1

The excreted quantity (mg per 96 h; mean ± SEM) of d0-γ-T, d0-, d3-, and d6-α-T. Fecal data were compared within subjects using a paired t-test (mean ± SEM; P values are shown for 40% compared with 0% fat, n = 6, subjects 1–5, 8). Molecular weights for d0-γT = 417, d0-α-T = 430, d3-α-T = 433, and d6-α-T = 436 g/mol.

2

Percent dose d3-α-T excreted = mg d3-α-T excreted/30 mg × 100.

3

d3-α-T fractional absorption = 100% – percent dose d3-α-T excreted.

4

Percent dose d6-α-T excreted = mg d6-α-T excreted/30 mg × 100.