. Author manuscript; available in PMC: 2020 Jun 14.

Published in final edited form as: Nephron. 2019 Jun 14;143(3):211–216. doi: 10.1159/000501207

Table 2.

Histological features associated with acute interstitial nephritis

Interstitial feature	Severity	Adj. OR (95% CI)
Interstitial infiltrate	<10%	1 (ref.)
	11–25%	4.1 (1.0, 17.2)
	>25%	17.6 (3.4, 90.4)
Eosinophils	0/HPF	1 (ref.)
	1–5/HPF	8.1 (2.1, 30.8)
	>5/HPF	71.3 (4.3, 1172.2)
Tubulitis	None	1 (ref.)
	1–5/tubule	9.7 (1.8, 53.8)
Tubular injury	<10%	1 (ref.)
	11–25%	0.4 (0.0, 3.5)
	>25%	0.1 (0.0, 1.3)

HPF, high power field; adj. OR, adjusted odds ratio

Logistic regression model for outcome of AIN and predictors as various interstitial histological features reported by the adjudicating pathologists controlling for the pathologist and clustered at participant level.