Table 2.
Time from brain death to cross clamp | ||||
---|---|---|---|---|
Variable | < 22 hours | 22–42 hours | > 42 hours | p-value |
(n=2,112) | (n=12,621) | (n=8,227) | ||
Male gender | 73.9% (1,560) | 71.0% (8,958) | 70.2% (5,777) | 0.004 |
Donor age (median, IQR) | 29 (19) | 30 (19) | 30 (19) | < 0.001 |
Donor BMI (median, IQR) | 26.3 (6.7) | 26.3 (7.1) | 26.2 (7.0) | 0.943 |
Donor ethnicity | < 0.001 | |||
White | 76.9% (1,625) | 68.9% (8,691) | 56.2% (4,627) | |
Black | 11.2% (236) | 15.7% (1,983) | 17.8% (1,462) | |
Hispanic | 9.9% (21p) | 12.9% (1,633) | 22.0% (1,814) | |
Other | 1.9% (41) | 2.5% (314) | 3.9% (324) | |
Donor history | ||||
Cigarette use | 15.9% (336) | 14.6% (1,845) | 11.2% (923) | < 0.001 |
Cocaine use | 16.1% (339) | 16.4% (2,071) | 18.5% (1,518) | < 0.001 |
Alcohol abuse | 14.0% (295) | 15.6% (1,970) | 16.6% (1,367) | 0.008 |
Diabetes | 2.6% (55) | 3.4% (435) | 3.4% (277) | 0.135 |
Hypertension | 12.0% (254) | 14.8% (1,862) | 15.7% (1,291) | < 0.001 |
Cancer | 1.5% (32) | 1.5% (192) | 1.4% (118) | 0.875 |
Donor creatinine (median, IQR) | 1.0 (0.6) | 1.0 (0.6) | 1.0 (0.7) | < 0.001 |
Donor bilirubin (median, IQR) | 0.8 (0.9) | 0.7 (0.7) | 0.7 (0.7) | < 0.001 |
Donor sodium (median, IQR) | 147 (11) | 148 (12) | 148 (11) | < 0.001 |
Donor ejection fraction (%, median, IQR) | 60 (10) | 60 (10) | 60 (8) | < 0.001 |
Prerecovery steroids | 80.2% (1,693) | 76.4% (9,646) | 70.2% (5,774) | < 0.001 |
Prerecovery T4 | 71.7% (1,515) | 74.0% (9,342) | 67.3% (5,537) | < 0.001 |
Donor cause of death | < 0.001 | |||
Anoxia | 20.7% (437) | 22.1% (2,787) | 26.9% (2,216) | |
Cerebrovascular/stroke | 19.6% (415) | 20.5% (2,588) | 19.7% (1,623) | |
Head trauma | 57.0% (1,203) | 54.6% (6,891) | 50.3% (4,141) | |
CNS tumor | 0.6% (13) | 0.6% (80) | 0.6% (50) | |
Other | 2.1% (44) | 2.2% (275) | 2.4% (197) | |
ABO blood type | 0.059 | |||
A | 38.7% (818) | 36.0% (4,549) | 35.5% (2,922) | |
B | 10.4% (220) | 11.1% (1,407) | 10.9% (899) | |
AB | 2.2% (46) | 2.4% (308) | 2.1% (169) | |
O | 48.7% (1,028) | 50.4% (6,357) | 51.5% (4,237) | |
Graft ischemic time (median hours, IQR) | 3.0 (1.4) | 3.2 (1.4) | 3.2 (1.4) | < 0.001 |
IQR, interquartile range; CNS, central nervous system