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. 2019 Feb 21;104(11):2314–2323. doi: 10.3324/haematol.2019.216101

Figure 5.

Figure 5.

Immuno-characterization of the T lymphocytes present in bone marrow aspirates of patients who either did or did not experience graft failure (GF). (A) Flow cytometry analysis of CD4+ and CD8+ population in patients with GF and controls (CTRL). Distribution of naïve (CD45RA+/CCR7+), central memory (CD45RO+/CCR7+), effector memory (CD45RO+/CCR7−), effector terminal (CD45RA+/CCR7−), and NK-T (CD3+/CD56+) subsets in CD4+ (B) or CD8+ (C) T cells. Activation and exhaustion profile in both the CD4+ and CD8+ population by the analysis of CD95 (D), CD127 (E), and CD57 (F). (A, D, E, and F) Each patient or CTRL is represented by a symbol and a horizontal line marks the median. (B and C) The average (+) and Median±Standard Deviation are shown. *P<0.05; **P<0.01; ***P<0.001; ****P<0.0001.