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. 2019 Oct 24;13:1138. doi: 10.3389/fnins.2019.01138

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Copyright © 2019 Qi, Yu, Fu, Liu, Gao, Tu, Kang, Shi, Li, Li and Kang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of ExT or PVN infusion of TAK242 on renal sympathetic nerve activity (RSNA) in 2K1C hypertensive rats and SHAM rats. (A) Original tracings of RSNA. (B) Statistic of RSNA. 2K1C hypertensive rats had higher RSNA than in SHAM rats. ExT or PVN infusion of TAK242 attenuated RSNA of 2K1C rats. ^∗P < 0.05 versus SHAM rats (SHAM + Sed + PVN vehicle, SHAM + ExT + PVN vehicle or SHAM + Sed + PVN TAK242). ^†P < 0.05 (2K1C + ExT + PVN vehicle or 2K1C + Sed + PVN TAK242) versus 2K1C + Sed + PVN vehicle.