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. 2019 Oct 30;9:15587. doi: 10.1038/s41598-019-52046-3

Table 2.

Cox proportional hazards regression measured hazard ratio of breast cancer.

Event Crude Adjusted
(n = 111) HR (95% CI) p-value HR (95% CI) p-value
Non-lactational mastitis
No 74 Ref. Ref.
Yes 37 1.94 (1.31–2.87) 0.001 1.94 (1.30–2.90) 0.001
Age at baseline
<40 42 Ref. Ref.
40–49 42 2.96 (1.93–4.54) <0.001 2.60 (1.63–4.14) <0.001
50–59 18 3.04 (1.75–5.28) <0.001 2.67 (1.43–4.96) 0.002
≥60 9 2.92 (1.42–6.01) 0.004 2.66 (1.14–6.21) 0.023
Monthly income (NT$)
0–15840 38 Ref. Ref.
15841–28800 52 2.01 (1.32–3.05) 0.001 1.42 (0.91–2.22) 0.127
28801–45800 14 2.02 (1.09–3.72) 0.025 1.34 (0.71–2.55) 0.370
>45800 7 3.41 (1.52–7.63) 0.003 2.41 (1.05–5.53) 0.038
Baseline comorbidity
Schizophrenia 6 2.46 (1.08–5.6) 0.032 2.66 (1.16–6.09) 0.021
Hypertension 18 1.68 (1.02–2.79) 0.044 0.91 (0.5–1.67) 0.773
Chronic obstructive pulmonary disease 16 1.54 (0.91–2.63) 0.108 1.15 (0.66–2.00) 0.611
Thyroid disease 6 0.71 (0.31–1.62) 0.416 0.58 (0.25–1.32) 0.194
Diabetes 13 1.75 (0.98–3.12) 0.059 1.19 (0.61–2.32) 0.611
Hyperlipidemia 19 1.64 (1–2.68) 0.051 0.98 (0.54–1.77) 0.939
Obesity 0
Medication
Hormonal medication 56 1.06 (0.73–1.55) 0.745 1.00 (0.68–1.48) 0.982

*Abbreviation: HR, hazard ratio; CI, confidence interval.

*Adjusted HR: adjusted for age, income, comorbidities and medication in Cox proportional hazards regression.