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. 2019 Oct 30;9:15587. doi: 10.1038/s41598-019-52046-3

Table 3.

Incidence rate, hazard ratio of breast cancer in different stratification.

Comparison Non-lactational mastitis Non-lactational mastitis vs Comparison
n = 12364 n = 3091 Crude HR Adjusted HR
Event Person years IR Event Person years IR (95% CI) (95% CI)
Overall 74 97722 7.57 37 25010 14.79 1.94 (1.31–2.87)** 1.94 (1.30–2.90)**
Age at baseline
<40 26 62439 4.16 16 16168 9.90 2.36 (1.27–4.4)** 2.22 (1.18–4.18)*
40–49 28 21294 13.15 14 5245 26.69 2.00 (1.05–3.81)* 2.12 (1.11–4.04)*
50–59 14 9061 15.45 4 2454 16.30 1.03 (0.34–3.12) 1.28 (0.41–4.02)
≥60 6 4928 12.18 3 1143 26.25 2.21 (0.55–8.84) 1.80 (0.43–7.48)
Monthly income (NT$)
0–15840 23 51975 4.43 15 12952 11.58 2.63 (1.37–5.04)** 2.60 (1.34–5.07)**
15841–28800 36 33946 10.61 16 8886 18.01 1.66 (0.92–3.00) 1.68 (0.93–3.06)
28801–45800 9 9125 9.86 5 2420 20.67 2.05 (0.69–6.12) 2.02 (0.66–6.16)
>45800 6 2676 22.42 1 753 13.29 0.59 (0.07–4.86) 0.53 (0.06–4.99)
Baseline comorbidity
Schizophrenia 5 2227 22.46 1 622 16.07 0.67 (0.08–5.76) 0.84 (0.09–7.60)
Hypertension 12 9988 12.01 6 2997 20.02 1.60 (0.60–4.27) 1.63 (0.60–4.42)
Chronic obstructive pulmonary disease 11 9861 11.16 5 2766 18.07 1.61 (0.56–4.65) 1.39 (0.47–4.05)
Thyroid disease 5 7414 6.74 1 2144 4.66 0.67 (0.08–5.72) 0.61 (0.07–5.47)
Diabetes 10 7023 14.24 3 1913 15.68 1.08 (0.30–3.91) 1.05 (0.28–3.85)
Hyperlipidemia 14 11089 12.63 5 3099 16.13 1.24 (0.45–3.46) 1.16 (0.41–3.25)
Obesity 0 1064 0.00 0 320 0.00
Medication
Hormonal medication 33 45423 7.27 23 16143 14.25 1.93 (1.13–3.28)* 1.96 (1.15–3.34)*

*Abbreviation: IR, incidence rates, per 10,000 person-years; HR, hazard ratio; CI, confidence interval.

*Adjusted HR: adjusted for age, income, comorbidities and medication in Cox proportional hazards regression.

*p-value < 0.05 *p-value < 0.01**.