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. 2019 Oct 30;10:4939. doi: 10.1038/s41467-019-12718-0

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Central pore inside OLPVRII pentamer. a Overall central pore structure. One protomer is hidden for clarity. The lipid fragment is colored violet. b View from the cytoplasmic side on the water pentagon and interaction network between water molecules and the pore-lining OLPVRII residues. c Side view of the pore vestibule. Example of 2Fo-Fc electron density map is shown around the water pentagon and the hydrocarbon chain. The map is contoured at the level of 1.2σ. The hydrocarbon chain is colored violet