Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Oct 30;9:15582. doi: 10.1038/s41598-019-52103-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Bacterial KEGG metabolic pathways affected by treatment with liraglutide and GUB09-145. Heatmap depicting bacterial KEGG modules with changes over the course of liraglutide and GUB09-145 treatment. Left heatmap: Spearman correlations between change in individual species abundance and various metabolic parameters affected by treatment, including plasma total cholesterol (TC), fasting glucose level on treatment day 14 (Fasting glucose), fasting terminal insulin levels (fasting insulin), glucose area-under the curve in an oral glucose tolerance test on treatment day 27 (AUC glucose OGTT), terminal plasma total triglycerides (TG), endpoint body weight loss relative to baseline (Body weight loss), and total caloric intake during the treatment period (Total caloric intake). Asterisks denote significant correlation (FDR-corrected, p < 0.05) between species and relevant metabolic parameter. Right heatmap: Fold change (log₂ transformed) in species abundance in individual mice as compared to baseline.