Fig. 2.

Phosphorylated E2F1 interacts with p300 and CBP in response to DNA damage. a GST-TopBP1 (BRCT1-6) or GST control protein were incubated with whole-cell extract from wild-type (WT) or E2f1^S29A/S29A (S29A) MEFs that were either untreated (−) or treated (+) with IR (10 Gy) and associated proteins were identified 2 h post-IR by western blot analysis. b A similar GST-TopBP1 pull-down assay was performed using extracts from parental U2OS cells or cells knocked down for RB, either untreated (−) or treated (+) with IR (10 Gy). Source data of a and b are provided as Supplementary Data 5