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. 2019 Oct 30;9:15580. doi: 10.1038/s41598-019-52082-z

Table 1.

Demographic and clinical parameters in PAD patients (n = 262).

PAD (n = 262) IC n = 147 CLI n = 115 p vs IC
Demographic and clinical data
   Sex (male, %) 87 88 85 0.442
   Age (years) 70 (11) 68 (10) 73 (11) <0.001
   Smokers (%)
     Never 20 12 29 0.004
     Current 32 35 29
     Former 48 53 42
   Diabetes mellitus (%) 53 36 74 <0.001
   Hypertension (%) 74 72 77 0.331
   Dyslipidemia (%) 62 67 57 0.093
   BMI (kg/m2) 28 (5) 28 (5) 28 (6) 0.830
   ABI 0.55 (0.19) 0.62 (0.17) 0.38 (0.13) <0.001
Personal history (%)
   COPD 14 14 13 0.772
   CKD 39 24 58 <0.001
   AMI 28 26 30 0.486
   Cardiomyopathy 25 14 38 <0.001
   Cerebral ischemia 9 5 14 0.009
Treatment (%)
   Anticoagulants 13 8 20 0.005
   Antiplatelets 77 82 70 0.033
   ACE inhibitors 34 32 36 0.440
   ARA-2 27 23 32 0.102
   Calcium antagonists 22 18 27 0.071
   Vasodilators 7 6 8 0.589
   β-Blockers 24 24 23 0.722
   Statins 65 69 59 0.084
Laboratory data
   Total col (mg/mL) 172 (46) 187 (41) 153 (47) <0.001
   LDL-C (mg/dL) 110 (91) 114 (83) 104 (99) 0.360
   HDL-C (mg/dL) 43 (16) 49 (15) 36 (13) <0.001
   Triglycerides (mg/dL) 145 (81) 151 (88) 138 (70) 0.194
   hs-CRPa (mg/mL) 5 (11) 3 (4) 10 (22) <0.001
   AST (U/L) 21 (9) 21 (9) 20 (8) 0.194
   ALT (U/L) 21 (14) 22 (14) 19 (13) 0.081
   GGT (U/L) 54 (69) 50 (61) 60 (78) 0.244
   eGFR (mL/min/1.73 m2) 73 (21) 79 (19) 66 (22) <0.001

Mean (SD) is shown. aLog-transformed variables are presented as median (interquartile range). BMI: body mass index, ABI: ankle-brachial index, COPD: chronic obstructive pulmonary disease, CKD: chronic kidney disease, AMI: acute myocardial infarction, ACE: angiotensin-converting enzyme, ARA-2: angiotensin II receptor antagonist, LDL: low-density lipoprotein, HDL: high-density lipoprotein. ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma glutamyltransferase; GFR: Glomerular filtration rate.