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. 2019 Oct 30;9:15699. doi: 10.1038/s41598-019-52155-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Amino acid comparison of human macaque, cattle and sheep PrP amino acid sequences. Only amino acids 89 to 238 (according to human PrP) are included in the comparison for clarity. Points indicate identical residues. Deletions are indicated by dashes. Amino acid numbering is indicated on the right. Species are named on the left. Amino acid changes in 166 and 168 positions (M/V and E/Q respectively) are boxed.