Skip to main content
. 2019 Sep 19;3(4):311–330. doi: 10.7150/ntno.38954

Figure 5.

Figure 5

(a, b) Intracellular uptake of different DOX-loaded dendrimers by (a) HBMEC and (b) U87-MG cells detected by flow cytometry. Dendrimers were incubated with the cells for 2 h before flow cytometry measurement. Cells without treatment were used as control. Error bars represent standard deviation (n=5). **p < 0.01, ***p < 0.001, ****p < 0.0001 (Student's t-test). (c, d) Subcellular trafficking of different DOX formulations in (c) HBMEC and (d) U87-MG cells detected by LSCM. Cells were incubated with Cy5.5-labeled different dendrimers for 2 h at the dendrimer concentration of 1 μM. LysoTracker Green DND-26 was used to stain lysosomes at the concentration of 0.1 μM. Hoechst was used to stain nucleus. Scale bar: 50 μm.