Table 1. Summary of 1q triplication in patients with MPN.
| Patient, age (yr)/sex | Diagnosis | Triplication region | Additional chromosomal abnormalities | Presence of another clonal marker | Reference |
|---|---|---|---|---|---|
| 38/F | PMF | trp(1)(q21q32) in all 20 metaphase cells | None | None (by AML gene panel test) | Present study |
| 28/M | CML (follow-up period) | trp(1)(q24q41) in all 20 metaphase cells | t(9;22)(q34;q11.2) in all 20 metaphase cells analyzed | NA | Park, et al. [2] |
| 57/F | CML → PMF | trp(1)(q21q32) in 6/22 metaphase cells | None | NA | Park, et al. [2] |
Abbreviations: MPN, myeloproliferative neoplasm; F, female; M, male; PMF, primary myelofibrosis; AML, acute myeloid leukemia; CML, chronic myeloid leukemia; NA, not available.