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. 2019 Oct 24;10:1031. doi: 10.3389/fgene.2019.01031

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Copyright © 2019 Liu, Meng, Li, Shen, Wang, Shan, Qiu, Zhang and Cheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immunohistochemistry of the five key genes based on the Human Protein Atlas. (A) Protein levels of CDCA5 in tumor tissue (staining: low; intensity: weak; quantity: > 75%). Protein levels of CDCA5 in normal tissue (staining: not detected; intensity: weak; quantity: < 25%). (B) Protein levels of FOXM1 in tumor tissue (staining: high; intensity: strong; quantity: > 75%). Protein levels of FOXM1 in normal tissue (staining: medium; intensity: moderate; quantity: 75–25%);. (C) Protein levels of KIF15 in tumor tissue (staining: medium; intensity: moderate; quantity: > 75%). Protein levels of KIF15 in normal tissue (staining: not detected; intensity: weak; quantity: < 25%). (D) Protein levels of MCM2 in tumor tissue (staining: high; intensity: strong; quantity: > 75%). Protein levels of MCM2 in normal tissue (staining: medium; intensity: moderate; quantity: 75–25%). (E) Protein levels of ZWINT in tumor tissue (staining: high; intensity: strong; quantity: > 75%). Protein levels of ZWINT in normal tissue (staining: low; intensity: weak; quantity: > 75%).