Figure 1. Metabolite Associations With Future Coronary Heart Disease.

Five phosphatidylcholine metabolites were associated with future coronary heart disease after Bonferroni correction. Hazard ratios (HR) are per SD of log-transformed metabolite level and are adjusted for body mass index, systolic blood pressure, antihypertensive treatment, diabetes, total cholesterol, sex, daily smoker status, study center, and examination age. Error bars indicate 95% CIs. The log-metabolite levels were multiplied by −1 to obtain HRs greater or equal to 1. Thus, HRs are described as HRs per a 1-SD decrease. A logarithmic scale is used on the x-axis. PC indicates phosphatidylcholine.