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. 2019 Jul 21;22(10):665–674. doi: 10.1093/ijnp/pyz041

Figure 2.

Figure 2.

The effects of (R)-ketamine and (S)-ketamine on extracellular monoamine levels in the prefrontal cortex (PFC) of lipopolysaccharide (LPS)-treated mice. Mice were i.p. injected with LPS (0.5 mg/kg) 24 hours before the experiment. (R)-Ketamine (20 mg/kg), (S)-ketamine (20 mg/kg), or saline was i.p. injected at 0 minutes (arrow). Results are expressed as the mean ± SEM of 5 mice per group. *P < .05, **P < .01, compared with saline-treated mice at each time point. #P < .05, ##P < .01, compared with (S)-ketamine-treated mice at each time point.