Table 1.

Raw Scores, Effect Sizes, and T Scores of HAMD-17^a, Core Factor Subscale^b, and Anxiety/Somatization Subscale^c at Each Assessment

	Assessment 1 (n = 116)	Assessment 2 (n = 116)	Assessment 3 (n = 107)	Assessment 4 (n = 73)	Assessment 5 (n = 61)
HAMD-17, mean ± SDd	30.9 ± 7.0	18.3 ± 7.6	11.1 ± 6.3	8.4 ± 5.9	7.1 ± 5.2
Effect size		1.59	2.34	2.76	2.77
Pe		<.001	<.001	<.001	<.001
Core factor subscale, mean ± SD	12.8 ± 3.1	7.6 ± 3.6	4.2 ± 3.2	2.9 ± 3.0	2.4 ± 2.7
Effect size		1.41	2.21	2.73	2.63
Pe		<.001	<.001	<.001	<.001
Anxiety/somatization subscale, mean ± SD	9.0 ± 3.0	5.7 ± 3.1	3.7 ± 2.3	2.8 ± 2.3	2.6 ± 2.0
Effect size		1.29	1.83	2.15	2.40
Pe		<.001	<.001	<.001	<.001
HAMD-17 T-score, mean ± SD	50.0 ± 10.0	32.0 ± 10.8	21.8 ± 9.0	17.9 ± 8.4	16.0 ± 7.5
Core factor subscale T-score, mean ± SD	50.0 ± 10.0	33.4 ± 11.4	22.5 ± 10.3	18.4 ± 9.6	16.8 ± 8.7
Anxiety/somatization subscale T-score, mean ± SD	50.0 ± 10.0	39.3 ± 10.1	32.7 ± 7.5	29.5 ± 7.7	28.9 ± 6.6

^aHAMD-17 = 17-item Hamilton Depression Rating Scale.

^bCore factor subscale = HAMD-17 Items 1(depressed mood), 2 (feelings of guilt), 3 (suicide), 7 (work and activities-loss of interest or pleasures), and 8 (motor retardation).

^cAnxiety/somatization subscale = HAMD-17 Items 10 (psychic anxiety), 11 (somatic anxiety), 12 (gastrointestinal somatic symptoms), 13 (general somatic symptoms), 15 (hypochondriasis), and 17 (insight).

^dSD = standard deviation.

^ePaired t test = mean scores at the assessments 2, 3, 4, and 5 compared with mean scores at assessment 1.