Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Dietary glycative-stress induced accumulation of AGEs. Under low glycemia diets (LG, left), intracellular proteolytic pathways are involved in the clearance of AGEs to preserve cellular function. During normal aging or under high glycemia diets (HG, right), proteolytic capacities are insufficient and AGEs accelerate the formation of aggregates/oligomers, leading to the onset of age-related diseases.
