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. 2019 Oct 30;50:87. doi: 10.1186/s13567-019-0707-2

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The Bayesian Skyline plot (BSP) of H3N8 CIV in each segment. BSPs were simulated using the BEAST (V1.8.4) program, based on all eight segments of 44 strains, with a GTR plus gamma nucleotide substitution mode and relaxed molecular clock. The prior tree set as the coalescent: Bayesian skyline with 10⁸ generations. The blue vertical bar indicates the period of divergence of major H3N8 lineages in canine species.