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. 2019 Oct 30;16:196. doi: 10.1186/s12974-019-1589-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Evidence of infiltrating monocyte contribution in the motor cortex of prpTDP-43^A315T-UeGFP mice. a A representative image of motor cortex of WT-UeGFP mice showing an infiltrating monocyte (CCR2+) within the blood vessel (CD31+), see arrowheads. c, d A representative image of motor cortex of prpTDP-43^A315T-UeGFP mice showing higher numbers of infiltrating monocytes (CCR2+) within the blood vessel (CD31+), see arrowheads and insets enlarged bellow in E, F. g, h A representative image of motor cortex of prpTDP-43^A315T-UeGFP mice showing infiltrating monocytes (CCR2+) that lack TMEM119 expression within the blood vessel. Inset is enlarged to the right. Scale bar = 20 μm