Figure 1.

T0901317 increases the expression of LXRα. hMSC were pretreated during 16 h with T0901317 and treated for 24 h with T0901317 in the absence of Palm (white column) or in the presence of Palm 0.25 mM (gray column), Ole 0.25 mM (shaded column). LXRα (A), LXRβ (B), expression were quantified by qPCR using the ΔΔCT method. Values were normalized for HPRT1 expression and are expressed as the ΔΔCT relative to control (Ctrl). Results are mean ± SEM of 9-12 individual experiments. ^*p < 0.01; ^**p < 0.001 vs. Ctrl; ^##p < 0.001 vs. Palm 0.25 mM.