Table 2.
Factors associated with positive sputum culture after 6 months of anti-TB treatment
| Sputum status at the end of anti-TB treatment | aP-value | |||
|---|---|---|---|---|
| Smear negative n/N (%) | Culture negative n/N (%) |
Culture positive n/N (%) |
||
| Age, years | ||||
| 16–35 | 144/144 (100) | 136/144 (94.4) | 8/144 (5.6) | .708 |
| 36–55 | 44/44 (100) | 40/44 ((90.9) | 4/44 (9.1) | .999 |
| 56–76 | 16/16 (100) | 16/16 (100) | 0/16 (0) | .998 |
| Male | 94/94 (100) | 88/94 (93.6) | 6/94 (6.3) | .585 |
| Female | 109/109 (100) | 103/109 (93.5) | 6/109 (5.5) | |
| Smoker | 14/204 (6.8) | 14/14 (100) | 0/14 (0) | .999 |
| Diabetes | 11/204 (5.3) | 11/11 (100) | 0/11 (0) | .999 |
| bBacillary load before treatment | ||||
| Scanty | 20/204 (9.8) | 18/20 (90.0) | 2/20 (10.0) | .661 |
| + 1 | 117/204 (57.4) | 109/117 (93.2) | 8/117 (6.8) | .382 |
| + 2 | 37/204 (18.1) | 36/37 (97.3) | 1/37 (2.7) | .661 |
| + 3 | 30/204 (14.7) | 29/30 (96.7) | 1/30 (3.3) | .815 |
| Smear positivity at 2 M | 3/204 (1.5) | 3/3 (100) | 0/3 (0) | 1.00 |
| Chest X-ray | ||||
| Cavitary lesions | 7/102 (6.9) | 6/7 (85.7) | 1/7 (14.3) | .265 |
| Non-cavitary infiltrates | 95/102 (93.1) | 91/95 (95.8) | 4/95 (4.2) | |
| History of contact | ||||
| cRecent | 41/204 (20.0) | 36/41 (87.8) | 5/41 (12.2) | .08 |
| dPrevious | 39/204 (19.2) | 39/39 (100) | 0/39 (100) | .998 |
| No history of contact | 124/204 (60.8) | 119/124 (95.9) | 5/124 (4.1) | .897 |
| Income | ||||
| Low | 109/204 (53.4) | 102/109 (93.6) | 7/109 (6.4) | .985 |
| Middle | 9/204 (4.5) | 9/9 (100) | 0/9 (0) | .862 |
| Unknown | 86/204 (42.1) | 81/86 (94.2) | 5/86 (5.8) | .999 |
| Medicines in the continuation Phase | ||||
| INH + Rifampicin | 103/204 | 4/103 (3.9) | 99/103 (96.1) | .177 |
| INH+ Rifampicin +Ethambutol | 101/204 | 8/101 (7.9) | 93/101 (92.1) | |
n number, N Total number, % percentage
aDifference between culture positive and culture negative groups
bGraded as per the guidelines of the International Union Against Tuberculosis and Lung Disease
cHistory of contact with active TB case during the course of diagnosis and treatment
dHistory of contact with active TB case before diagnosis and treatment