Table 2.
SYRCLE Risk of Bias Assessment for included studies
| Author (Year) | Random sequence generation? | Groups similar at baseline? | Allocation concealed? | Animals randomly housed? | Blinding of caregivers and/or examiners? | Random selection for outcome assessment? | Blinding of outcome assessor? | Incomplete outcome data addressed? | Free from selective outcome reporting? | Free from other bias? |
|---|---|---|---|---|---|---|---|---|---|---|
| Ahmadi (2017) | Yes | Yes | Unclear | Unclear | Unclear | Yes | Unclear | Yes | Yes | Yes |
| Ahmadi (2016) | Yes | Yes | Unclear | Unclear | Unclear | Unclear | Unclear | Yes | Yes | Yes |
| Aslam (2009) | Unclear | No | Unclear | Unclear | Unclear | Unclear | Unclear | Yes | Yes | Yes |
| Cruz (2015) | Unclear | Yes | Unclear | Unclear | Unclear | Unclear | Unclear | Yes | No | Yes |
| Ionescu (2012) | Unclear | Yes | Unclear | Unclear | Unclear | Unclear | Unclear | Yes | Yes | Yes |
| Lee (2012) | Unclear | Unclear | Unclear | Unclear | Unclear | Unclear | Unclear | Yes | Yes | Yes |
| Lu (2015) | Unclear | Yes | Unclear | Unclear | Unclear | Unclear | Unclear | Yes | Yes | Yes |
| Rathinasabapathy (2016) | Unclear | Yes | Yes | Unclear | Yes | Yes | Yes | Yes | Yes | Yes |
| Sutsko (2012) | Unclear | No | Unclear | Unclear | Unclear | Yes | Yes | Yes | Yes | Yes |
| Wakayama (2015) | Unclear | Yes | Unclear | Unclear | Unclear | Yes | Unclear | Yes | Yes | Yes |