Table 2. Subgroup analysis of OS.
Variables | Studies (n) | HR, 95%CI | P | Heterogeneity | Model | |
---|---|---|---|---|---|---|
I2 (%) | P | |||||
Sample size (n) | ||||||
≤60 | 3 | 2.07 (1.34, 3.21) | <0.01* | 0 | 0.60 | Fixed |
>60 | 4 | 3.10 (1.47, 6.55) | <0.01* | 65 | 0.04 | Random |
Cut-off value | ||||||
Median | 6 | 2.26 (1.66, 3.07) | <0.01* | 0 | 0.61 | Fixed |
Mean | 1 | 8.95 (3.56, 22.50) | <0.01* | NA | NA | Fixed |
Cancer type | ||||||
NSCLC | 2 | 2.82 (1.90, 4.18) | <0.01* | 0 | 0.55 | Fixed |
Others | 5 | 2.34 (1.06, 5.16) | 0.03* | 62 | 0.03 | Random |
Abbreviation: NA, not available.
*P<0.05 indicating significant association between GHET1 expression and OS.