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. 2019 Oct 18;39(10):BSR20181740. doi: 10.1042/BSR20181740

Figure 2. DGT participated in the expression of IKK and the activity of NF-κB regulated by HG via GAS5.

Figure 2

(A) SV40 MES-13 cells were transfected with si-GAS5 or si-control. Then, SV40 MES-13 cells were divided into normal glucose (NG) group, HG group, HG+DGTXT (10%) group, HG+DGTXT (10%)+si-control group, HG+DGTXT (10%)+si-GAS5 group. The expressions of IKK were detected in NG group, HG group, HG+DGTXT (10%) group, HG+DGTXT (10%)+si-control group, HG+DGTXT (10%)+si-GAS5 group. (B) The luciferase activity of IKK was measured in NG group, HG group, HG+DGTXT (10%) group, HG+DGTXT (10%)+si-control group, HG+DGTXT (10%)+si-GAS5 group. ** P<0.01, compared with NG group. ##P<0.01, compared with HG group. &P<0.01, compared with HG+ DGTXT+si-control group.