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. 2019 Oct 18;39(10):BSR20181740. doi: 10.1042/BSR20181740

Figure 5. DGT inhibited the proliferation of HG-induced mesangial cells and accumulation of extracellular matrix via GAS5.

Figure 5

SV40 MES-13 cells were transfected with si-control or si-GAS5. Then, SV40 MES-13 cells were divided into NG group, HG group, HG+DGTXT group, HG+DGTXT+si-control group, HG+DGTXT+si-GAS5 group. (A) The proliferation of SV40 MES-13 cells was detected in NG group, HG group, HG+DGTXT group, HG+DGTXT+si-control group, HG+DGTXT+si-GAS5 group. (B) The levels of LN, FN and Col IV were detected in NG group, HG group, HG+DGTXT group, HG+DGTXT+si-control group, HG+DGTXT+si-GAS5 group. ** P<0.01, compared with NG. ##P<0.01, compared with HG. &P<0.01, compared with HG+DGTXT+si-control.