Figure 4. CDR3 lengths and BCR heavy-chain variant frequencies in the peripheral blood of IgAN patients and HCs.
(A) The peripheral blood BCR heavy-chain repertoire in terms of CDR3 length in HCs and IgAN patients (P=1.02e-06); (B) the peripheral blood IgAN variant frequencies of genes encoding BCR heavy chains in IgAN patients and HCs. Abbreviations: NB, peripheral blood of IgAN patients; Nor, peripheral blood of HCs; NT, tissue of IgAN patients.