Table 3. IgAN disease characteristics in terms of the four types of BCR heavy-chain CDR3 sequences.
CDR3 | Freq SN | Average frequency in peripheral blood | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
17 | 35 | 24 | 1 | 3 | 5 | 10 | 40 | 2 | 7 | 16 | 19 | 27 | 34 | 28 | ||
ALYFHNSAY | 3687 | 24663 | 2 | 94793 | 24 | 23871 | 4249 | 801 | 27423 | 0 | 18 | 3784 | 29293 | 53845 | 2 | 4399 |
ARWGPMYYYMDV | 1321 | 713 | 2 | 71095 | 97034 | 0 | 4970 | 29382 | 27423 | 0 | 41207 | 1267 | 29293 | 12 | 86739 | 10058 |
ARDQGALNA | 28268 | 201 | 31433 | 3 | 86 | 0 | 50827 | 476 | 110 | 0 | 4 | 15795 | 6 | 2 | 2 | 5238 |
ARVDNPADF | 2542 | 49327 | 31433 | 23698 | 3 | 0 | 5704 | 29382 | 27423 | 0 | 10 | 3248 | 4 | 26923 | 86739 | 4971 |