Table 3. Comparative analysis according to antiplatelet medication on admission before propensity-score matching.
p-value <0.05; n (%), p-value: Chi2 test; mean (±SD), p-value: two-sample T-test; median (IQR), p-value: Mann-Whitney U test
SBP: Systolic blood pressure; WFNS: World Federation of Neurosurgical Societies; GCS: Glasgow coma scale; SAH: subarachnoid hemorrhage; IPH: intraparenchymal hemorrhage; CHF: cardiac heart failure; EVD: external ventricular drain; VP: ventriculoperitoneal; DCI: delayed cerebral ischemia; mRS: modified Rankin scale
| Variables | Antiplatelets | p-Value | |
| No 229 (85.8%) | Yes 38 (14.2%) | ||
| Age | 55.5 (±13.9) | 68.5 (±13.8) | <0.001 |
| Gender | |||
| Female | 151 (65.9%) | 26 (68.4%) | 0.76 |
| Male | 78 (34.1%) | 12 (31.6%) | |
| Smoking | 77 (42.3%) | 10 (32.3%) | 0.29 |
| Chronic hypertension | 102 (46.4%) | 27 (71.0%) | 0.005 |
| Anticoagulation on presentation | 3 (1.3%) | 1 (2.6%) | 0.53 |
| Aneurysm morphology | |||
| Saccular | 213 (93.0%) | 35 (92.1%) | 0.84 |
| Fusiform | 16 (7.0%) | 3 (7.9%) | |
| Circulation location | |||
| Anterior | 178 (77.7%) | 31 (81.6%) | 0.59 |
| Posterior | 51 (22.3%) | 7 (18.4%) | |
| Aneurysm Max. Size (mm) | 5 (IQR 3 .8 - 7) | 5 (IQR 4 - 8) | 0.89 |
| Multiple aneurysms | 3 (1.3%) | 0 (0.0%) | 0.48 |
| SBP on admission | 137.8 (±26.4) | 137.1 (±21.6) | 0.89 |
| SBP on admission ≥140 | 90 (46.1%) | 17 (53.1%) | 0.46 |
| WFNS | |||
| 1 | 106 (46.5%) | 14 (36.8%) | 0.25 |
| 2 | 21 (9.2%) | 4 (10.5%) | |
| 3 | 2 (0.9%) | 2 (5.3%) | |
| 4 | 32 (14.0%) | 7 (18.4%) | |
| 5 | 67 (29.4%) | 11 (28.9%) | |
| Hunt & Hess | |||
| 1 | 46 (20.1%) | 9 (23.7%) | 0.85 |
| 2 | 62 (27.1%) | 7 (18.4%) | |
| 3 | 43 (18.8%) | 8 (21.0%) | |
| 4 | 42 (18.3%) | 7 (18.4%) | |
| 5 | 36 (15.7%) | 7 (18.4%) | |
| Hunt & Hess (4-5) | 78 (34.1%) | 14 (36.8%) | 0.74 |
| Modified Fisher | |||
| 1 | 11 (4.8%) | 1 (2.6%) | 0.44 |
| 2 | 13 (5.7%) | 0 (0%) | |
| 3 | 61 (26.6%) | 11 (28.9%) | |
| 4 | 144 (62.9%) | 26 (68.4%) | |
| GCS | 14 (IQR 6 - 15) | 13.5 (IQR 6 - 15) | 0.61 |
| Severe | 87 (38.2%) | 17 (44.7%) | 0.63 |
| Moderate | 12 (5.3%) | 1 (2.6%) | |
| Mild | 129 (56.6%) | 20 (52.6%) | |
| SAH thickness (mm) | 6.8 (IQR 4.96 - 9.13) | 7.52 (IQR 5.98 - 10.1) | 0.08 |
| Cerebral edema | 28 (12.3%) | 6 (15.0%) | 0.63 |
| IPH presence | 47 (20.5%) | 9 (23.7%) | 0.66 |
| Volume IPH (mL3) | 8.14 (IQR 2.66 - 18.06) | 8.57 (IQR 2.58 - 19.56) | 0.68 |
| Seizure during hospitalization | 19 (9.05%) | 3 (8.8%) | 0.97 |
| Cardiac abnormality in first 24 hours | 9 (3.9%) | 3 (7.9%) | 0.27 |
| Hydrocephalus on admission | 108 (47.4%) | 17 (44.7%) | 0.76 |
| EVD in first 24 hours | 122 (53.3%) | 25 (65.8%) | 0.15 |
| VP shunt placement | 38 (16.6%) | 7 (18.4%) | 0.78 |
| Aneurysm management | |||
| Medical | 21 (9.2%) | 5 (13.2%) | 0.17 |
| Microsurgical clipping | 36 (15.7%) | 6 (15.8%) | |
| Endovascular | 170 (74.2%) | 25 (65.8%) | |
| Clipping+Endovascular | 2 (0.9%) | 2 (5.3%) | |
| Cerebral infarction due to DCI | 33 (14.4%) | 6 (15.8%) | 0.82 |
| mRS at discharge | |||
| 0 to 2 | 154 (67.3%) | 17 (44.7%) | 0.007 |
| 3 to 6 | 75 (32.7%) | 21 (55.3%) | |