Table 4. Genotype of three SNPs within the EPAS1 gene and differences in SpO2 value in different populations.
| SpO2 (%) SNP sites | Wild type | Heterozygous mutation | Homozygous mutation | |
|---|---|---|---|---|
| Plain group | rs13419896 | 97.30 ± 1.36 | 97.08 ± 1.60 | 99.11 ± 1.64 |
| rs1868092 | 97.33 ± 1.37 | 97.00 ± 2.00 | 95.69 ± 3.56 | |
| rs4953354 | 97.02 ± 1.53 | 97.92 ± 1.31 | 98.55 ± 1.41 | |
| Plateau (3 days) | rs13419896 | 87.44 ± 3.37 | 87.81 ± 3.29 | 87.62 ± 1.60 |
| rs1868092 | 87.85 ± 3.16 | 86.64 ± 2.84 | – | |
| rs4953354 | 87.76 ± 3.05 | 87.15 ± 3.41 | – | |
| Plateau (30 days) | rs13419896 | 90.40 ± 2.46 | 90.18 ± 2.96 | 91.81 ± 1.41 |
| rs1868092 | 90.06 ± 2.62 | 91.86 ± 1.77 | – | |
| rs4953354 | 90.31 ± 2.84 | 90.56 ± 1.24 | – | |
| Plateau (>10 years) | rs13419896 | 88.75 ± 7.09 | 87.20 ± 5.45 | 92.30 ± 5.24 |
| rs1868092 | 89.62 ± 5.37 | 80.04 ± 3.25 | 86.39 ± 4.12 | |
| rs4953354 | 83.00 ± 4.24 | 93.00 ± 2.55 | 84.09 ± 3.46 | |
| Native Tibetans | rs13419896 | 95.00 ± 1.23 | 94.15 ± 2.64 | 94.65 ± 2.30 |
| rs1868092 | 94.33 ± 2.08 | 94.00 ± 2.04 | 94.97 ± 2.54 | |
| rs4953354 | 96.00 ± 1.73 | 94.07 ± 2.46 | 94.60 ± 2.34 |