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. 2019 Oct 31;14(10):e0223919. doi: 10.1371/journal.pone.0223919

Fig 2. Effects of eNOS on systemic serum cytokines and chemokines during disseminated candidiasis.

Fig 2

(A). Serum levels of the indicated proteins were assessed at 1 to 7 days PI for Nos3 -/- and WT mice infected i.v. with C. albicans. WT (small checkered bars) or Nos3 -/- (large checkered bars) data are presented as mean ± standard deviation for 7 mice per each group subjected to survival bleeding at each time point. (B) Serum levels of the indicated proteins were assessed in noninfected mice at day 0, and day 3, and 4 PI for WT and Nos3 -/- mice infected iv with C. albicans. Mean values at time 0 were determined using sera from 3 control mice, and other data are mean ± standard deviation for 3 mice at each time point. (* = p<0.05; ** = p<0.01; *** = p<0.001, **** = p<0.0001).