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. 2019 Nov 1;68(43):967–973. doi: 10.15585/mmwr.mm6843a3

TABLE 2. Percentage of opioid-involved overdose deaths* involving synthetic opioids among adults aged ≥18 years, by urbanization level, age group, and race/ethnicity, — National Vital Statistics System, United States, 2015–2017.

Urbanization level Age group (yrs) Race/Ethnicity§,¶ Year, %

2015 2016 2017 % Increase, 2015–2017**,††
Large central metro
All
Black
30.6
57.1
69.2
126
White
26.1
44.0
56.0
115
Hispanic
20.2
45.8
55.7
175
18–24
Black
33.8
48.2
70.8
109
White
29.8
44.9
59.9
101
Hispanic
17.1
40.6
56.4
230
25–34
Black
35.1
60.1
70.3
100
White
30.6
51.1
62.8
105
Hispanic
22.9
46.1
56.4
147
35–44
Black
27.8
55.4
66.5
139
White
27.8
49.8
61.5
121
Hispanic
20.2
50.6
59.2
193
45–54
Black
29.7
61.8
70.0
135
White
24.1
41.1
54.2
125
Hispanic
21.1
48.1
56.0
165
55–64
Black
31.8
55.0
69.9
120
White
20.7
32.7
44.9
117
Hispanic
17.2
41.1
47.5
176
≥65
Black
22.9
50.0
65.5
186
White
19.7
23.9
28.8
46
Hispanic
§§

46.3

Large fringe metro
All
Black
34.5
55.1
74.8
117
White
34.3
52.0
65.4
91
Hispanic
29.1
53.7
67.2
131
18–24
Black
41.7
64.4
70.5
69
White
37.8
56.1
70.9
88
Hispanic
32.3
51.1
64.2
99
25–34
Black
43.1
59.1
75.1
74
White
39.5
59.4
72.9
85
Hispanic
34.4
61.2
67.9
98
35–44
Black
35.6
56.0
79.1
122
White
36.1
55.1
69.4
92
Hispanic
27.7
54.6
71.0
156
45–54
Black
28.3
50.9
71.3
152
White
30.5
46.0
59.9
97
Hispanic
28.2
45.0
72.6
158
55–64
Black
30.3
50.7
74.5
146
White
24.5
37.7
48.9
100
Hispanic


50.7

≥65
Black


79.4

White
20.7
28.5
37.0
79
Hispanic




Medium and small metro All
Black
36.0
49.9
67.4
87
White
29.0
42.3
57.8
100
Hispanic
17.9
36.9
47.9
168
18–24
Black
58.3
47.4
65.1
12
White
34.3
45.9
66.0
92
Hispanic
25.6
36.4
53.2
108
25–34
Black
35.1
54.1
76.2
117
White
34.0
49.1
66.3
95
Hispanic
16.8
35.2
53.4
217
35–44
Black
37.7
51.8
69.7
85
White
31.0
46.6
62.8
102
Hispanic
20.1
44.6
51.1
154
45–54
Black
34.5
50.6
68.0
97
White
26.1
38.9
53.6
106
Hispanic
18.2
34.3
43.7
140
55–64
Black
30.3
47.1
58.8
94
White
21.6
28.6
43.0
99
Hispanic

31.2
32.5

≥65 Black


46.9

White
17.2
23.4
22.2
29
Hispanic

* Deaths were classified using the International Classification of Diseases, Tenth Revision (ICD-10). Opioid-involved overdose deaths were identified using underlying cause-of-death codes X40–44, X60–64, X85, and Y10–14. Among deaths with overdose as the underlying cause, the type of drug involved in the overdose death was indicated by the following ICD-10 multiple cause-of-death codes: any opioid (T40.0, T40.1, T40.2, T40.3, T40.4, or T40.6) and synthetic opioids other than methadone (T40.4). Totals for deaths by category might involve more than one drug other than synthetic opioids. The percentage of opioid-involved overdose deaths involving synthetic opioids was calculated by dividing the number of opioid-involved overdose deaths involving synthetic opioids by the number of opioid-involved overdose deaths, then multiplying by 100.

Based on the 2013 urbanization classification (https://www.cdc.gov/nchs/data_access/urban_rural.htm). Large central metro: counties in metropolitan statistical areas (MSAs) of ≥1 million population that 1) contain the entire population of the largest principal city of the MSA, or 2) have their entire population contained in the largest principal city of the MSA, or 3) contain at least 250,000 inhabitants of any principal city of the MSA. Large fringe metro: counties in the MSAs of ≥1 million population that did not qualify as large central metro counties. Medium metro: counties in MSAs of populations of 250,000–999,999. Small metro: counties in MSAs of populations <250,000. Because of low numbers of deaths and rate suppression for key populations, micropolitan areas (nonmetropolitan counties) and noncore areas (counties that did not qualify as micropolitan) were not included in this analysis.

§ Blacks and whites were non-Hispanic; Hispanics could be of any race.

Data for Hispanic origin should be interpreted with caution; studies comparing Hispanic origin on death certificates and on census surveys have indicated that reporting on Hispanic ethnicity is inconsistent. https://www.cdc.gov/nchs/data/series/sr_02/sr02_172.pdf.

** Percentage increase in opioid-involved overdose deaths involving synthetic opioids was calculated by subtracting the percentage of deaths that involved synthetic opioids in 2017 from the percentage of deaths involving synthetic opioids in 2015, dividing this value by the percentage of deaths involving synthetic opioids in 2015, and then multiplying by 100.

†† Total percent changes were rounded to the nearest whole number.

§§ Dashes indicate that percent change in synthetic opioid involvement in opioid-involved overdose deaths could not be calculated because of unreliable rates or suppression.