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. 2019 Aug 21;36(10):2866–2880. doi: 10.1007/s12325-019-01061-x

Table 5.

Barriers to participation in a clinical trial, all and by sex

Number one reason preventing participation All (n = 367) Male (n = 120) Female (n = 245)
n % n % n %
Potential side effects 127 34.6 45 37.5 82 33.5
Time required 56 15.3 17 14.2 38 15.5
Distance to trial site 37 10.1 12 10.0 25 10.2
Uncertainty regarding the benefit 29 7.9 13 10.8 16 6.5
Uncertainty regarding insurance coverage 26 7.1 3 2.5 22 9.0
Little awareness of trials 20 5.4 8 6.7 12 4.9
Inconvenience 18 4.9 7 5.8 11 4.5
Compensation 6 1.6 4 3.3 2 0.8
Hearing about someone else’s experience 5 1.4 0 0.0 5 2.0
Not interested 2 0.5 0 0.0 2 0.8
Other 41 11.2 11 9.2 30 12.2

Two participants who preferred not to indicate their sex were not included in the per-sex analysis