Table 1.
Study | Chemotherapy | Intervention | PFS (months) | PFS HR | OS (months) | OS HR |
---|---|---|---|---|---|---|
Reck et al. [23] | Carboplatin plus paclitaxel | Ipilimumab | 3.9 | 0.93 (059–1.48) | 9.1 | 0.89 (0.57–1.39) |
Placebo | 5.2 | 10.5 | ||||
Reck et al. [24] | Platinum plus etoposide | Ipilimumab | 4.6 | 0.85 (0.75–0.97) | 11.0 | 0.94 (0.81–1.09) |
Placebo | 4.4 | 10.9 | ||||
Horn et al. [25] | Carboplatin plus etoposide | Atezolizumab | 5.2 | 0.77 (0.62–0.96) | 12.3 | 0.70 (0.54–0.91) |
Placebo | 4.3 | 10.3 |