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. 2019 Jun 17;36(8):1826–1832. doi: 10.1007/s12325-019-01008-2

Table 1.

Select randomized trials featuring concurrent chemotherapy and immunotherapy

Study Chemotherapy Intervention PFS (months) PFS HR OS (months) OS HR
Reck et al. [23] Carboplatin plus paclitaxel Ipilimumab 3.9 0.93 (059–1.48) 9.1 0.89 (0.57–1.39)
Placebo 5.2 10.5
Reck et al. [24] Platinum plus etoposide Ipilimumab 4.6 0.85 (0.75–0.97) 11.0 0.94 (0.81–1.09)
Placebo 4.4 10.9
Horn et al. [25] Carboplatin plus etoposide Atezolizumab 5.2 0.77 (0.62–0.96) 12.3 0.70 (0.54–0.91)
Placebo 4.3 10.3