Table 1.
Demographic characteristics for evaluable subjects by menopausal status
| All evaluable subjects (N = 993) | Premenopausal subjects (N = 506) | Postmenopausal subjects (N = 487) | |
|---|---|---|---|
| Age, years | |||
| N | 993 | 506 | 487 |
| Mean (SD) | 50.3 (14.10) | 40.2 (8.67) | 60.8 (10.54) |
| Median | 49 | 42 | 60 |
| Range (min, max) | 18, 92 | 18, 60 | 33, 92 |
| Ethnicity | |||
| Asian | 22 (2.2) | 13 (2.6) | 9 (1.8) |
| Black or African American | 135 (13.6) | 92 (18.2) | 43 (8.8) |
| Native Hawaiian or Other Pacific Islander | 1 (0.1) | 1 (0.2) | 0 (0.0) |
| White | 741 (74.6) | 334 (66.0) | 407 (83.6) |
| Other | 8 (0.8) | 5 (1.0) | 3 (0.6) |
| Hispanic or Latino | 86 (8.7) | 61 (12.1) | 25 (5.1) |
| Pathology diagnosis, n (%) | |||
| Benign ovarian conditions | 748 (75.3) | 433 (85.6) | 315 (64.7) |
| Malignant conditions | 245 (24.7) | 73 (14.4) | 172 (35.3) |
| Epithelial ovarian cancer | 150 (15.1) | 41 (8.1) | 109 (22.4) |
| Other primary ovarian malignancies (not EOC) | 16 (1.6) | 8 (1.6) | 8 (1.6) |
| Low malignant potential (borderline) | 42 (4.2) | 12 (2.4) | 30 (6.2) |
| Non-primary ovarian malignancies with involvement of the ovaries | 23 (2.3) | 8 (1.6) | 15 (3.1) |
| Non-primary ovarian malignancies with no involvement of ovaries | 14 (1.4) | 4 (0.8) | 10 (2.1) |
| Histology (% of EOC and other primary) | |||
| Epithelial: serous | 76 (45.8) | 18 (36.7) | 58 (49.6) |
| Epithelial: mucinous | 17 (10.2) | 5 (10.2) | 12 (10.3) |
| Epithelial: endometroid | 23 (13.9) | 11 (22.4) | 12 (10.3) |
| Epithelial: clear cell | 12 (7.2) | 3 (6.1) | 9 (7.7) |
| Epithelial: transitional | 2 (1.2) | 0 (0.0) | 2 (1.7) |
| Epithelial: carcinosarcoma | 6 (3.6) | 1 (2.0) | 5 (4.3) |
| Epithelial: mixed | 2 (1.2) | 1 (2.0) | 1 (0.9) |
| Epithelial: undifferentiated | 2 (1.2) | 0 (0.0) | 2 (1.7) |
| Epithelial: other | 10 (6.0) | 2 (4.1) | 8 (6.8) |
| Non-epithelial: sex cord stromal | 7 (4.2) | 3 (6.1) | 4 (3.4) |
| Non-epithelial: germ cell | 2 (1.2) | 0 (0.0) | 2 (1.7) |
| Non-epithelial: other | 7 (4.2) | 5 (10.2) | 2 (1.7) |
| Stage (% of EOC and other primary) | |||
| Stage I | 59 (35.5) | 18 (36.7) | 41 (35.0) |
| Stage II | 25 (15.1) | 10 (20.4) | 15 (12.8) |
| Stage III | 72 (43.4) | 18 (36.7) | 54 (46.2) |
| Stage IV | 8 (4.8) | 2 (4.1) | 6 (5.1) |
| Not given | 2 (1.2) | 1 (2.0) | 1 (0.9) |
|
Grade (% of EOC and other primary) Serous grade 3 |
61 (36.7) | 15 (30.6) | 46 (39.3) |
| Other grade 3 | 39 (23.5) | 10 (20.4) | 29 (24.8) |
| Grade 2 | 35 (21.1) | 13 (26.5) | 22 (18.8) |
| Grade 1 | 20 (12.0) | 8 (16.3) | 12 (10.3) |
| Not given | 11 (6.6) | 3 (6.1) | 8 (6.8) |
Menopausal status imputed when not stated time from last menstruation (> 12 months = postmenopausal; < 6 months = premenopausal). If between 6 and 12 months or the time is not given, then premenopausal imputed from when aged ≤ 50; postmenopausal when aged > 50