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. 2019 Jun 5;36(8):2034–2051. doi: 10.1007/s12325-019-00965-y

Table 4.

Long-term cost-effectiveness outcomes in the base case analysis

Health outcomes Once-weekly semaglutide 0.5 mg Dulaglutide 1.5 mg Difference
Discounted life expectancy (years) 11.61 (0.15) 11.57 (0.15) + 0.04
Discounted quality-adjusted life expectancy (QALYs) 7.19 (0.09) 7.16 (0.10) + 0.04
Discounted direct costs (EUR) 18,686 (399) 18,706 (404) − 20
ICER based on life expectancy and direct costs Once-weekly semaglutide 0.5 mg dominant
ICER based on quality-adjusted life expectancy and direct costs Once-weekly semaglutide 0.5 mg dominant
Health outcomes Once-weekly semaglutide 1 mg Dulaglutide 1.5 mg Difference
Discounted life expectancy (years) 11.63 (0.15) 11.57 (0.15) + 0.06
Discounted quality-adjusted life expectancy (QALYs) 7.23 (0.10) 7.16 (0.10) + 0.07
Discounted direct costs (EUR) 18,566 (402) 18,706 (404) − 140
ICER based on life expectancy and direct costs Once-weekly semaglutide 1 mg dominant
ICER based on quality-adjusted life expectancy and direct costs Once-weekly semaglutide 1 mg dominant

Values are means (standard deviations)

EUR euros, ICER incremental cost-effectiveness ratio, QALYs quality-adjusted life years