Table 1.
Treatment-effect modifiers selected for analysis
| Factor | Treatment effect modifier? | ||
|---|---|---|---|
| CR/CRi | HSCT | OS/EFS | |
| Age | Yes | Yes | Yes |
| Philadelphia chromosome status | Yes | No | Yes |
| Prior HSCT | Yes | Yes | Yes |
| Duration of first remission | Yes | No | No |
| Prior number of salvage therapies | Yes | No | No |
| Maximum of central/local bone marrow blasts | Yes | No | No |
| Geographical region | No | Yes | Yes |
CR complete response, CRi complete remission with incomplete hematologic recovery, EFS event-free survival, HSCT hematopoietic stem cell transplantation, OS overall survival