Table 1.
Patient characteristics
| Characteristic | R/R total (N = 707) | R/R with HSCT (n = 476) | R/R without HSCT (n = 231) |
|---|---|---|---|
| Age, mean years (SD) | 52.0 (12.5) | 51.2 (11.6) | 53.6 (13.9) |
| Sex, n (%) male | 377 (53.3) | 258 (54.2) | 119 (51.5) |
| Geographic region, n (%) | |||
| Northeast | 175 (24.8) | 123 (25.8) | 52 (22.5) |
| Midwest | 211 (29.8) | 149 (31.3) | 62 (26.8) |
| South | 264 (37.3) | 170 (35.7) | 94 (40.7) |
| West | 57 (8.1) | 34 (7.1) | 23 (10.0) |
| Payer type, n (%) | |||
| Commercial | 440 (62.2) | 300 (63.0) | 140 (60.6) |
| Self-insured | 245 (34.7) | 167 (35.1) | 78 (33.8) |
| Medicare risk | 5 (0.7) | 1 (0.2) | 4 (1.7) |
| Medicaid | 11 (1.6) | 5 (1.1) | 6 (2.6) |
| Unknown | 6 (0.8) | 3 (0.6) | 3 (1.3) |
| Charlson Comorbidity Index (CCI), mean (SD) | 0.9 (1.4) | 0.9 (1.3) | 1.1 (1.5) |
| Baseline comorbid conditions, n (%) | |||
| Asthma | 36 (5.1) | 24 (5.0) | 12 (5.2) |
| Cardiac arrhythmia | 46 (6.5) | 27 (5.7) | 19 (8.2) |
| Chronic pain/fibromyalgia | 40 (5.7) | 23 (4.8) | 17 (7.4) |
| Depression | 39 (5.5) | 25 (5.3) | 14 (6.1) |
| Diabetes | 78 (11.0) | 47 (9.9) | 31 (13.4) |
| Dyslipidemia | 201 (28.4) | 142 (29.8) | 59 (25.5) |
| Hypertension | 218 (30.8) | 137 (28.8) | 81 (35.1) |
| Liver/gallbladder/pancreatic disease | 36 (5.1) | 22 (4.6) | 14 (6.1) |
| Myocardial infarction/CAD | 51 (7.2) | 27 (5.7) | 24 (10.4) |
| Osteoarthritis | 161 (22.8) | 110 (23.1) | 51 (22.1) |
| Sleep disorders | 47 (6.6) | 37 (7.8) | 10 (4.3) |
| Smoking or history of smoking | 61 (8.6) | 36 (7.6) | 25 (10.8) |
| Thyroid disease | 50 (7.1) | 34 (7.1) | 16 (6.9) |
CAD coronary artery disease, HSCT hematopoietic stem cell transplantation, R/R relapsed/refractory