Table 3.
Demographic features, radiologic findings, and clinical outcomes in poor-grade SAH patients
| Control (N = 177) | Cerebrolysin (N = 69) | p value | |
|---|---|---|---|
| Female sex | 117 (66.1%) | 45 (65.2%) | 1.000 |
| Age | 56.0 [49.0; 68.0] | 56.0 [50.0; 65.0] | 0.599 |
| Operation type | |||
| Clip | 129 (72.9%) | 51 (73.9%) | 0.997 |
| Coil | 48 (27.1%) | 18 (26.1%) | |
| Circulation | |||
| Anterior | 153 (86.4%) | 63 (91.3%) | 0.406 |
| Posterior | 24 (13.6%) | 6 (8.7%) | |
| Hunt and Hess grade | |||
| Grade 3 | 93 (52.5%) | 34 (49.3%) | 0.286 |
| Grade 4 | 79 (44.6%) | 30 (43.5%) | |
| Grade 5 | 5 (2.8%) | 5 (7.2%) | |
| Modified Fisher scale | |||
| 1 | 4 (2.3%) | 3 (4.3%) | 0.133 |
| 2 | 3 (1.7%) | 3 (4.3%) | |
| 3 | 53 (29.9%) | 12 (17.4%) | |
| 4 | 117 (66.1%) | 51 (73.9%) | |
| GCS score | 11.0 [6.0; 13.0] | 8.0 [6.0; 13.0] | 0.447 |
| Concomitant ICH | 71 (40.1%) | 33 (47.8%) | 0.339 |
| Bicaudate index | 18.1 [15.3; 21.3] | 15.7 [13.7; 18.8] | 0.001* |
| SAH sum score | 25.0 [14.0; 27.0] | 27.0 [23.0; 29.0] | 0.001* |
| IVH sum score | 2.0 [0.0; 5.0] | 2.0 [1.0; 4.0] | 0.994 |
| Smoking | 46 (26.0%) | 18 (26.1%) | 1.000 |
| Hypertension | 80 (45.2%) | 25 (36.2%) | 0.257 |
| Diabetes mellitus | 14 (7.9%) | 7 (10.1%) | 0.757 |
| Permanent shunt | 32 (18.1%) | 16 (23.2%) | 0.466 |
| Angiographic vasospasm | 51 (28.8%) | 36 (52.2%) | 0.001 |
| Delayed cerebral ischemia | 25 (14.1%) | 16 (23.2%) | 0.128 |
| Days of Cerebrolysin | 0.0 [0.0; 0.0] | 14.0 [12.0; 21.0] | |
| Length of stay (days) | 30.0 [15.0; 67.0] | 33.0 [16.0; 70.0] | 0.547 |
| mRS | 4.0 [2.0; 6.0] | 4.0 [2.0; 5.0] | 0.525 |
| Clinical outcome | |||
| Favorable (mRS 0–2) | 62 (35.0%) | 20 (29.0%) | 0.452 |
| Unfavorable (mRS 3–6) | 115 (65.0%) | 49 (71.0%) | |
| Mortality | 45 (25.4%) | 6 (8.7%) | 0.006* |
SAH subarachnoid hemorrhage, GCS Glasgow Coma Scale, ICH intracerebral hemorrhage, IVH intraventricular hemorrhage, mRS modified Rankin Scale
*Indicates statistical significance (p < 0.05)