Table 6.

Conceptual framework for statin intolerance patient survey

Concept	Items for survey
Respondent demographics	Age Sex Marital status Education level Employment status
Clinical characteristics	Statin intolerant group (Y/N) Self-reported health status Comorbid conditions Perception of risk for myocardial infarction Diagnosis of familial hypercholesterolemia Family history of medical conditions History of non-statin side effects Knowing others who have discontinued a statin Current prescriptions per day Current over-the-counter medications per day Activity level Alcohol Smoking Patient Health Questionnaire (PHQ-4)
Health information and beliefs	Comfort level with Dr. Quality of communication with Dr. Type of Dr. providing prescribing statin Feels listened to by Dr. Willingness to try another statin Level of involvement with medical care decisions Satisfaction with information from Dr. Information sources (frequency of use, level of trust) Reason for taking a statin Reason for not taking a statin Cholesterol under control or not
Statin side effect history	Statins taken Current use of a statin or not Side effects with previous statin Type of side effects Side effects with current or most recent statin Time to onset of side effects Side effect interference with activities Type of changes made to address side effects Improvements after changes made Time to improvement Timing of most recent side effect experience Current over-the-counter supplement
Symptom severity	Muscle aches Muscle cramps Muscle pain Muscle soreness Muscle stiffness Muscle weakness Bone and joint pain Abdominal pain Lack of energy Tires easily Exhaustion Fatigue Memory problems Irritability Frustration
Impact severity	Needing to rest more Reduced ability to be physically active Limited social activities Increased office visits Reduced productivity or performance Reduced ability to exercise Trouble getting good quality sleep