Table 2.
HF (% ± SD) | LF (% ± SD) | Log2FC (± SE) | p-value | FDR | |
---|---|---|---|---|---|
Baseline visit: Family | |||||
S24_7 | 0.72 ± 1.81 | 1.01 ± 3.34 | −24.7 ± 3.04 | 4.7E-16 | 1.7E-14 |
Prevotellaceae | 7.60 ± 19.8 | 3.76 ± 12.5 | −8.72 ± 1.51 | 7.5E-09 | 1.3E-07 |
Rikenellaceae | 0.53 ± 1.03 | 2.18 ± 4.26 | 2.81 ± 1.00 | 0.005 | 0.05 |
Enterobacteriaceae | 1.89 ± 5.61 | 5.82 ± 12.7 | 3.55 ± 1.28 | 0.006 | 0.05 |
Peptostreptococcaceae | 0.09 ± 0.13 | 0.10 ± 0.25 | −2.25 ± 0.92 | 0.01 | 0.11 |
Genus | |||||
Barnesiella | 1.85 ± 4.67 | 0.00 ± 0.00 | −25.3 ± 2.74 | 2.4E-20 | 1.3E-18 |
Paraprevotella | 0.62 ± 1.64 | 0.00 ± 0.00 | −23.6 ± 3.04 | 7.7E-15 | 2.1E-13 |
Prevotella | 7.60 ± 19.8 | 3.76 ± 12.5 | −8.53 ± 1.51 | 1.4E-08 | 2.7E-07 |
Clostridium | 0.05 ± 0.05 | 0.41 ± 1.03 | 2.36 ± 0.74 | 0.001 | 0.02 |
Enterobacter | 0.00 ± 0.00 | 0.02 ± 0.06 | 4.80 ± 2.17 | 0.03 | 0.25 |
Alistipes | 0.34 ± 0.87 | 0.04 ± 0.05 | −2.64 ± 1.22 | 0.03 | 0.25 |
Adlercreutzia | 0.04 ± 0.09 | 0.08 ± 0.19 | 1.60 ± 0.75 | 0.03 | 0.25 |
Species | |||||
Barnesiella intestinihominis | 1.85 ± 4.67 | 0.00 ± 0.00 | −25.7 ± 3.04 | 2.7E-17 | 9.9E-16 |
1-month visit: Family | |||||
Paraprevotellaceae | 0.37 ± 1.05 | 0.00 ± 0.00 | −23.7 ± 3.04 | 6.6E-15 | 2.2E-13 |
Prevotellaceae | 6.93 ± 21.1 | 5.79 ± 19.2 | −8.32 ± 1.44 | 6.8E-09 | 1.1E-07 |
S24_7 | 0.38 ± 1.03 | 1.11 ± 3.69 | −7.18 ± 2.56 | 0.005 | 0.06 |
Genus | |||||
Prevotella | 6.93 ± 21.1 | 5.79 ± 19.2 | −9.00 ± 1.43 | 3.2E-10 | 1.8E-08 |
Barnesiella | 1.03 ± 2.47 | 0.00 ± 0.00 | −9.02 ± 3.04 | 0.003 | 0.08 |
Phascolarctobacterium | 0.37 ± 0.91 | 0.04 ± 0.14 | −8.64 ± 3.04 | 0.004 | 0.08 |
Species | |||||
Eubacterium biforme | 0.05 ± 0.14 | 0.21 ± 0.47 | 22.3 ± 3.01 | 1.4E-13 | 5.2E-12 |
Desulfovibrio D168 | 0.05 ± 0.19 | 0.22 ± 0.48 | 21.1 ± 3.02 | 2.6E-12 | 4.7E-11 |
Faecalibacterium prausnitzii | 1.00 ± 1.04 | 0.24 ± 0.29 | −2.29 ± 0.76 | 0.003 | 0.02 |
Barnesiella intestinihominis | 1.03 ± 2.47 | 0.00 ± 0.00 | −8.79 ± 2.93 | 0.003 | 0.02 |
Bacteroides caccae | 0.01 ± 0.02 | 0.00 ± 0.01 | −3.12 ± 1.13 | 0.006 | 0.04 |
Escherichia coli | 0.48 ± 1.03 | 4.32 ± 9.23 | 2.32 ± 1.20 | 0.05 | 0.29 |
Clostridium citroniae | 0.03 ± 0.05 | 0.02 ± 0.03 | −1.45 ± 0.76 | 0.05 | 0.29 |
Percent relative abundance (± SD) for family, genus, and bacterial species that are significantly different when comparing HF with LF older adults at baseline and at the 1-month study visits are shown in order of significance with log 2-fold change (Log2FC) values ± standard error (SE).