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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Exp Gerontol. 2019 Sep 4;127:110722. doi: 10.1016/j.exger.2019.110722

Table 3.

Percent relative abundance for bacteria that are significantly different when comparing HF with LF human fecal donors, and HF- with LF-colonized mice.

Human fecal donors Human-microbiome containing mice
HF (% ± SD) LF (% ± SD) Log2FC (± SE) p-value FDR HF-mice (% ± SD) LF-mice (% ± SD) Log2FC (± SE) p-value FDR
Phyla
Verrucomicrobia 0.06 ± 0.04 0.83 ± 3.27 6.47 ± 1.64 8.0E-05 0.0008 0.01 ± 0.03 6.12 ± 10.1 10.3 ± 1.83 1.9E-0.08 1.1E-07
Cyanobacteria 0.37 ± 0.55 0.00 ± 0.00 −8.68 ± 2.94 0.003 0.002 2.22 ± 4.04 0.00 ± 0.00 −9.10 ± 1.72 1.3E-07 4.0E-07
Class
4C0d_2 0.37 ± 0.55 0.00 ± 0.00 −9.67 ± 2.53 0.0001 0.001 2.22 ± 4.04 0.00 ± 0.00 −9.84 ± 1.28 1.9E-14 2.1E-13
Gammaproteobacteria 0.13 ± 0.16 9.54 ± 14.1 5.46 ± 1.44 0.0002 0.001 0.02 ± 0.03 0.19 ± 0.47 5.10 ± 1.46 0.0005 0.002
Verrucomicrobiae 0.06 ± 0.04 1.83 ± 3.27 5.70 ± 1.65 0.0005 0.003 0.01 ± 0.03 6.12 ± 0.00 10.4 ± 1.6 2.7E-10 1.5E-09
Order
YS2 0.37 ± 0.55 0.00 ± 0.00 −8.77 ± 2.55 0.0006 0.004 2.22 ± 4.04 0.00 ± 0.00 −9.84 ± 1.29 2.1E-14 2.6E-13
Verrucomicrobiales 0.06 ± 0.04 1.83 ± 3.27 6.45 ± 1.75 0.002 0.002 0.01 ± 0.03 6.12 ± 10.1 10.7 ± 1.84 5.6E-9 3.3E-08
Enterobacteriales 0.06 ± 0.05 9.33 ± 14.0 6.53 ± 1.67 9.2E-05 0.002 0.02 ± 0.03 0.19 ± 0.47 5.09 ± 1.46 0.0005 0.002
Family
Verrucomicrobiaceae 0.06 ± 0.04 1.83 ± 3.27 7.63 ± 1.83 2.9E-05 0.0002 0.01 ± 0.03 6.12 ± 10.1 9.48 ± 1.93 8.9E-07 6.8E-14
Prevotellaceae 4.72 ± 11.6 0.00 ± 0.00 −28.3 ± 3.00 4.6E-21 8.1E-20 1.11 ± 2.75 0.00 ± 0.00 −5.58 ± 1.94 0.004 0.02
Enterobacteriaceae 0.06 ± 0.05 9.33 ± 14.0 7.18 ± 1.72 3.0E-05 0.0002 0.02 ± 0.03 0.19 ± 0.47 3.77 ± 1.53 0.01 0.04
S24_7 2.05 ± 0.00 0.00 ± 0.00 27.1 ± 2.85 1.9E-21 6.6E-20 11.4 ± 19.3 1.23 ± 2.93 −4.27 ± 1.88 0.02 0.06
Erysipelotrichaceae 0.15 ± 0.26 1.50 ± 2.04 2.83 ± 1.30 0.03 0.15 1.25 ± 2.86 3.69 ± 7.58 1.49 ± 0.68 0.03 0.06
Genus
Paraprevotella 1.78 ± 2.76 0.00 ± 0.00 −27.6 ± 3.00 3.9E-20 1.1E-18 1.40 ± 2.70 0.00 ± 0.00 −27.3 ± 2.34 2.1E-31 6.9E-30
Akkermansia 0.06 ± 0.04 1.83 ± 3.27 5.67 ± 1.80 0.002 0.01 0.01 ± 0.03 6.12 ± 10.1 9.91 ± 1.82 5.1E-08 5.6E-07
Barnesiella 1.62 ± 3.46 0.00 ± 0.00 −26.3 ± 2.95 4.9E-19 8.9E-18 0.79 ± 1.63 0.00 ± 0.00 −8.37 ± 1.65 3.6E-07 3.0E-06
Eubacterium 0.00 ± 0.00 0.72 ± 0.84 6.98 ± 2.01 0.0005 0.004 0.01 ± 0.02 0.07 ± 0.07 4.44 ± 1.08 4.1E-05 0.0002
Prevotella 4.72 ± 11.6 0.00 ± 0.00 −28.7 ± 3.00 1.3E-21 7.0E-20 1.11 ± 2.75 0.00 ± 0.00 −6.58 ± 2.05 0.001 0.005
Coprobacillus 1.18 ± 1.26 2.16 ± 2.16 5.90 ± 3.01 0.05 0.15 0.12 ± 0.12 0.23 ± 0.22 1.46 ± 0.58 0.01 0.04
Species
Barnesiella intestinihominis 1.62 ± 3.46 0.00 ± 0.00 −28.7 ± 2.90 3.8E-23 1.2E-21 0.79 ± 1.63 0.00 ± 0.00 −25.6 ± 1.71 1.9E-50 4.1E-49
Akkermansia muciniphila 0.06 ± 0.04 1.83 ± 3.27 5.02 ± 1.87 0.007 0.03 0.01 ± 0.03 6.12 ± 10.1 8.40 ± 1.88 7.8E-06 4.3E-05

Percent relative abundance (± SD) for bacteria that are significantly different when comparing both the human fecal donors and their respectively colonized mice are shown with log 2-fold change (Log2FC) values ± standard error (SE).